Agaric acid reduces Salmonella biofilm formation by inhibiting flagellar motility

Flagellar motility is critical for Listeria monocytogenes biofilm formation.

The food-borne pathogen Listeria monocytogenes attaches to environmental surfaces and forms biofilms that can be a source of food contamination, yet little is known about the molecular mechanisms of its biofilm development. We observed that nonmotile mutants were defective in biofilm formation. To investigate how flagella might function during biofilm formation, we compared the wild type with f...

Biofilm Formation of Salmonella

Salmonella spp. may form biofilm, and bacteria in biofilm are more resistant to drug, chemical, physical and mechanical stresses, and host immune system. The progress on biofilm research will be helpful for the development of new tools and strategies to prevent biofilm-related disease and decontaminate biofilm-derived Salmonella in food produc‐ tion. In this review, we present a comprehensive o...

Listeria monocytogenes DNA Glycosylase AdlP Affects Flagellar Motility, Biofilm Formation, Virulence, and Stress Responses

UNLABELLED The temperature-dependent alteration of flagellar motility gene expression is critical for the foodborne pathogen Listeria monocytogenes to respond to a changing environment. In this study, a genetic determinant, L. monocytogenes f2365_0220 (lmof2365_0220), encoding a putative protein that is structurally similar to the Bacillus cereus alkyl base DNA glycosylase (AlkD), was identifie...

SadC reciprocally influences biofilm formation and swarming motility via modulation of exopolysaccharide production and flagellar function.

Pseudomonas aeruginosa has served as an important organism in the study of biofilm formation; however, we still lack an understanding of the mechanisms by which this microbe transitions to a surface lifestyle. A recent study of the early stages of biofilm formation implicated the control of flagellar reversals and production of an exopolysaccharide (EPS) as factors in the establishment of a sta...

Production and Flagellar Function Modulation of Exopolysaccharide Formation and Swarming Motility via SadC Reciprocally Influences Biofilm